Alosetron Oral is used to treat diarrhea, pain, cramps, and the feeling of an urgent need to have bowel movements caused by irritable bowel syndrome (IBS; a condition that causes stomach pain, bloating, constipation, and diarrhea) in women who have diarrhea as their main symptom and have not been helped by other treatments.
Lotronex should be used only by women with severe irritable bowel syndrome and diarrhea as the main symptom.
Do not start taking Lotronex if you are constipated. You also should not take alosetron if you take another medicine called fluvoxamine (Luvox).
Serious or fatal side effects on the stomach and intestines have occurred in some people taking Lotronex. In rare cases, Lotronex has caused severe constipation, or ischemic colitis (caused by reduced blood flow to the intestines).
Stop taking this medicine and call your doctor right away if you have: new or worsening constipation, stomach pain, bright or dark red blood in your stools, or bloody diarrhea. You may need to permanently discontinue this medicine if you have these side effects.
Do not start taking Lotronex if you are constipated. You also should not take taking this medicine if you take another medicine called fluvoxamine (Luvox).
If you stop taking this medicine for any reason, do not start taking it again without your doctor's advice.